Vildagliptin-d7

• CAT Number: R067124
• CAS Number: 1133208-42-0
• Molecular Formula: C17H18D7N3O2
• Molecular Weight: 310.4
• Purity: ≥95%
• Synonyms: (2S)-1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidine-2,3,3,4,4,5,5-d7-carbonitrile
• Storage: 2°C to 8°C
• IUPAC Name: (2S)-2,3,3,4,4,5,5-heptadeuterio-1-[2-[(3-hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile
• InChI: InChI=1S/C17H25N3O2/c18-9-14-2-1-3-20(14)15(21)10-19-16-5-12-4-13(6-16)8-17(22,7-12)11-16/h12-14,19,22H,1-8,10-11H2/t12?,13?,14?,16-,17-/i1D2,2D2,3D2,14D
• InChIKey: SYOKIDBDQMKNDQ-IUSGACIYSA-N
• SMILES: O=C(CN[C@@]1(CC(C2)C3)CC3C[C@]2(O)C1)N4[C@]([2H])(C#N)C([2H])([2H])C([2H])([2H])C4([2H])[2H]

Vildagliptin-d7 is a deuterated form of Vildagliptin, featuring seven deuterium atoms. This high-purity isotopically labeled compound is crucial for advanced research in pharmacology and drug metabolism, particularly in the study of dipeptidyl peptidase-4 (DPP-4) inhibitors used in the treatment of type 2 diabetes. It is extensively utilized in mass spectrometry and other analytical techniques to investigate the pharmacokinetics, metabolic stability, and bioavailability of Vildagliptin in biological systems. The deuterium labeling ensures enhanced accuracy and sensitivity in quantitative analyses, making Vildagliptin-d7 an invaluable tool for researchers focused on optimizing diabetes therapies and understanding the detailed metabolic pathways of DPP-4 inhibitors.