Vincristine-d3 Sulfate

For research use only. Not for therapeutic Use.

  • CAT Number: R011943
  • CAS Number: 1217854-24-4
  • Molecular Formula: C₄₆H₅₅D₃N₄O₁₄S
  • Molecular Weight: 926.05
  • Purity: ≥95%
Inquiry Now

Vincristine-d3 Sulfate is a deuterated form of vincristine sulfate, a potent chemotherapeutic agent used in cancer treatment, particularly for leukemia and lymphoma. The deuterium labeling enhances the stability and precision of analytical studies using techniques like NMR and mass spectrometry. Vincristine-d3 Sulfate functions by inhibiting microtubule formation, thereby disrupting mitotic spindle formation and cell division. This compound is used in pharmaceutical research to investigate drug metabolism, pharmacokinetics, and to improve therapeutic strategies. It also helps in understanding the behavior and interactions of vincristine in complex biological systems.


Catalog Number R011943
CAS Number 1217854-24-4
Synonyms

22-Oxovincaleukoblastine-d3 Sulfate; Leurocristine-d3 Sulfate; Kyocristine-d3; Lilly 37231-d3; NSC 67574-d3; Novopharm-d3; Oncovin-d3; Onkovin-d3; VCR Sulfate-d3; Vincasar PFS-d3; Vincrisul-d3;

Molecular Formula C₄₆H₅₅D₃N₄O₁₄S
Purity ≥95%
Target Cytoskeleton
Storage -20°C
IUPAC Name methyl (1R,9R,10S,11R,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-(trideuteriomethoxycarbonyl)-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate;sulfuric acid
InChI InChI=1S/C46H56N4O10.H2O4S/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6;1-5(2,3)4/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3;(H2,1,2,3,4)/t28-,37+,38-,39-,42+,43-,44-,45+,46+;/m1./s1/i5D3;
InChIKey AQTQHPDCURKLKT-XHFXVLIGSA-N
SMILES [2H]C([2H])([2H])OC(=O)[C@@]1(C[C@H]2C[C@](CN(C2)CCC3=C1NC4=CC=CC=C34)(CC)O)C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC.OS(=O)(=O)O

Request a Quote