Viomycin

• CAT Number: I010821
• CAS Number: 32988-50-4
• Molecular Formula: C25H43N13O10
• Molecular Weight: 685.70
• Purity: ≥95%
• Synonyms: (S)-3,6-Diamino-N-((3S,9S,12S,15S,Z)3((2R,4S)-6-amino-4-hydroxy-1,2,3,4-tetrahydropyridin-2-yl)-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-6-(ureidomethylene)-1,4,7,10,13-pentaazacyclohexadecan-15-yl)hexanamide disulfate
• Target: Antibiotic
• Solubility: Soluble to 75 mM in water
• Storage: Store at -20C
• IUPAC Name: (3S)-3,6-diamino-N-[(3S,6Z,9S,12S,15S)-3-[(4R,6S)-2-amino-6-hydroxy-1,4,5,6-tetrahydropyrimidin-4-yl]-6-[(carbamoylamino)methylidene]-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentazacyclohexadec-15-yl]hexanamide
• InChI: InChI=1S/C25H43N13O10/c26-3-1-2-10(27)4-16(41)32-12-6-30-23(47)18(11-5-17(42)37-24(28)36-11)38-20(44)13(7-31-25(29)48)33-21(45)14(8-39)35-22(46)15(9-40)34-19(12)43/h7,10-12,14-15,17-18,39-40,42H,1-6,8-9,26-27H2,(H,30,47)(H,32,41)(H,33,45)(H,34,43)(H,35,46)(H,38,44)(H3,28,36,37)(H3,29,31,48)/b13-7-/t10-,11+,12-,14-,15-,17-,18-/m0/s1
• InChIKey: GXFAIFRPOKBQRV-GHXCTMGLSA-N
• SMILES: C1[C@@H](N=C(N[C@H]1O)N)[C@H]2C(=O)NC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N/C(=C\NC(=O)N)/C(=O)N2)CO)CO)NC(=O)C[C@H](CCCN)N

Viomycin（Cat No.:I010821）is an antibiotic primarily used in the treatment of multi-drug resistant tuberculosis (MDR-TB). It works by inhibiting bacterial protein synthesis through binding to the 16S rRNA of the ribosome, disrupting the translation process. This action prevents the growth of Mycobacterium tuberculosis, the bacterium responsible for tuberculosis. Viomycin is considered a second-line therapy, used when first-line drugs are ineffective or unavailable. While effective against certain strains, its use is often limited by potential side effects such as nephrotoxicity and ototoxicity, requiring careful monitoring during treatment.