Virginiamycin-S1

• CAT Number: R000520
• CAS Number: 23152-29-6
• Molecular Formula: C43H49N7O10
• Molecular Weight: 823.90
• Purity: ≥95%
• Target: Bacterial
• Solubility: Soluble in DMSO
• Storage: Store at -20°C
• IUPAC Name: N-[(3S,6S,12R,15S,16R,19S,22S)-3-benzyl-12-ethyl-4,16-dimethyl-2,5,11,14,18,21,24-heptaoxo-19-phenyl-17-oxa-1,4,10,13,20-pentazatricyclo[20.4.0.06,10]hexacosan-15-yl]-3-hydroxypyridine-2-carboxamide
• InChI: InChI=1S/C43H49N7O10/c1-4-29-40(56)49-21-12-17-30(49)41(57)48(3)32(23-26-13-7-5-8-14-26)42(58)50-22-19-28(51)24-31(50)37(53)47-35(27-15-9-6-10-16-27)43(59)60-25(2)34(38(54)45-29)46-39(55)36-33(52)18-11-20-44-36/h5-11,13-16,18,20,25,29-32,34-35,52H,4,12,17,19,21-24H2,1-3H3,(H,45,54)(H,46,55)(H,47,53)/t25-,29-,30+,31+,32+,34+,35+/m1/s1
• InChIKey: FEPMHVLSLDOMQC-IYPFLVAKSA-N
• SMILES: CC[C@@H]1C(=O)N2CCC[C@H]2C(=O)N([C@H](C(=O)N3CCC(=O)C[C@H]3C(=O)N[C@H](C(=O)O[C@@H]([C@@H](C(=O)N1)NC(=O)C4=C(C=CC=N4)O)C)C5=CC=CC=C5)CC6=CC=CC=C6)C

Virginiamycin-S1（Cat No.:R000520）is a high-purity antibiotic compound used primarily in pharmaceutical research and the study of antimicrobial resistance. A member of the streptogramin class of antibiotics, Virginiamycin-S1 functions by inhibiting bacterial protein synthesis, specifically targeting the 50S ribosomal subunit. It exhibits potent activity against Gram-positive bacteria, including multi-drug-resistant strains, and is often employed in combination therapies to enhance efficacy. Virginiamycin-S1 is essential for investigations into novel antimicrobial agents and the development of resistance-modifying strategies. Its stable properties make it a reliable reagent for laboratory applications in microbiology and infectious disease research.

Reference

The structures of the minor components of virginiamycin S. Vanderhaeghe, H. et al. , Tet. Lett. 1971, 2687.Virginiamycin: nomenclature. Crooy P. and De Neys R. J. Antibiot. 1972, 25, 371.A new species of Streptomyces producing virginiamycin family antibiotics. Ogata, K. et al. , J. Antibiot. 1978, 31, 1313.