For research use only. Not for therapeutic Use.
Viscumneoside III, a dihydroflavone O-glycoside, is a potent tyrosinase inhibitor with an IC50 of 0.5 mM. Viscumneoside III has anti-angina pectoris[1].
Viscumneoside III (1.0 mg/mL) has the inhibition activitie on tyrosinase of 77% . Viscumneoside III is used as a material for cosmetics with whitening function[1].
| Catalog Number | M023103 |
| CAS Number | 118985-27-6 |
| Synonyms | (2S)-7-[(2S,3R,4S,5S,6R)-3-[(2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-2,3-dihydrochromen-4-one |
| Molecular Formula | C27H32O15 |
| Purity | ≥95% |
| InChI | InChI=1S/C27H32O15/c1-37-17-4-11(2-3-13(17)30)16-7-15(32)20-14(31)5-12(6-18(20)40-16)39-25-23(22(34)21(33)19(8-28)41-25)42-26-24(35)27(36,9-29)10-38-26/h2-6,16,19,21-26,28-31,33-36H,7-10H2,1H3/t16-,19+,21+,22-,23+,24-,25+,26-,27+/m0/s1 |
| InChIKey | BYALYZGUSBVZQP-XJBIVIJWSA-N |
| SMILES | COC1=C(C=CC(=C1)C2CC(=O)C3=C(C=C(C=C3O2)OC4C(C(C(C(O4)CO)O)O)OC5C(C(CO5)(CO)O)O)O)O |
| Reference | [1]. LeiZou, et al. Total synthesis of viscumneoside III of Viscum coloratum. Tetrahedron,Volume 74, Issue 19, 10 May 2018,Pages 2376-2382. [2]. Se-Hui Jung, et al. Velutin, an Aglycone Extracted from Korean Mistletoe, with Improved Inhibitory Activity against Melanin Biosynthesis. Molecules. 2019 Jul 12;24(14):2549. |
