For research use only. Not for therapeutic Use.
VK-II-36 is a carvedilol analog that suppresses sarcoplasmic reticulum Ca2+release but does not block the β-receptor.VK-II-36 inhibits triggered activities evoked by both early and delayed after depolarizations[1].
| Catalog Number | I012139 |
| CAS Number | 955371-66-1 |
| Synonyms | 6-(9H-carbazol-4-yloxymethyl)-4-[2-(2-methoxyphenoxy)ethyl]morpholin-3-one |
| Molecular Formula | C26H26N2O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C26H26N2O5/c1-30-22-10-4-5-11-23(22)31-14-13-28-15-18(32-17-25(28)29)16-33-24-12-6-9-21-26(24)19-7-2-3-8-20(19)27-21/h2-12,18,27H,13-17H2,1H3 |
| InChIKey | OPUVSUMPCOUABG-UHFFFAOYSA-N |
| SMILES | COC1=CC=CC=C1OCCN2CC(OCC2=O)COC3=CC=CC4=C3C5=CC=CC=C5N4 |
| Reference | [1]. Maruyama M, et al. Carvedilol analogue inhibits triggered activities evoked by both early and delayed afterdepolarizations. Heart Rhythm. 2013 Jan;10(1):101-7. |
