Vortioxetine-d8 hydrobromide

• CAT Number: S000460
• Molecular Formula: C18H15D8BrN2S
• Molecular Weight: 387.41
• Purity: ≥95%
• IUPAC Name: 2,2,3,3,5,5,6,6-octadeuterio-1-[2-(2,4-dimethylphenyl)sulfanylphenyl]piperazine;hydrobromide
• InChI: InChI=1S/C18H22N2S.BrH/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20;/h3-8,13,19H,9-12H2,1-2H3;1H/i9D2,10D2,11D2,12D2
• InChIKey: VNGRUFUIHGGOOM-QPUNNWGTSA-N
• SMILES: CC1=CC(=C(C=C1)SC2=CC=CC=C2N3CCNCC3)C.Br

Vortioxetine-d8 hydrobromide（Cat No.:S000460） is a deuterated version of vortioxetine, where eight hydrogen atoms are replaced with deuterium, aimed at enhancing the drug’s metabolic stability for detailed pharmacokinetic studies. Vortioxetine is an antidepressant used for treating major depressive disorder. It works by modulating multiple serotonin receptors and inhibiting the serotonin transporter, thereby enhancing neurotransmitter levels in the brain to improve mood and cognitive function. The hydrobromide salt form enhances its solubility. The deuterated variant, Vortioxetine-d8 hydrobromide, allows researchers to delve into the intricate dynamics of the drug’s metabolism and efficacy in the body.