For research use only. Not for therapeutic Use.
VSN35111（Cat No.:I038123）is a specific product, part number, or code that may refer to a wide range of items, depending on the context. However, there is no widely recognized or standard reference to “VSN35111” available in major product catalogs or databases. It could be a model number for electronics, machinery, or a specific component in industries such as automotive, medical equipment, or technology. To provide a more accurate explanation, additional context or details are needed regarding the type of product or industry it belongs to.
| Catalog Number | I038123 |
| CAS Number | 797035-11-1 |
| Synonyms | BACE-1 Inhibitor; β-Secretase Inhibitor IV; BACE IV; VSN35111; VSN-35111; VSN 35111; Axon 1125; Axon-1125; Axon1125; |
| Molecular Formula | C31H38N4O5S |
| Purity | 98% |
| Target | Beta-secretase |
| Solubility | To be determined |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 3-N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl]-5-[methyl(methylsulfonyl)amino]-1-N-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide |
| InChI | InChI=1S/C31H38N4O5S/c1-21(23-12-8-5-9-13-23)33-30(37)24-17-25(19-27(18-24)35(2)41(3,39)40)31(38)34-28(16-22-10-6-4-7-11-22)29(36)20-32-26-14-15-26/h4-13,17-19,21,26,28-29,32,36H,14-16,20H2,1-3H3,(H,33,37)(H,34,38)/t21-,28+,29-/m1/s1 |
| InChIKey | VPNIQGRFZCTBEZ-SPTGULJVSA-N |
| SMILES | C[C@H](C1=CC=CC=C1)NC(=O)C2=CC(=CC(=C2)N(C)S(=O)(=O)C)C(=O)N[C@@H](CC3=CC=CC=C3)[C@@H](CNC4CC4)O |
| Reference | 1. Stachel, S.J., Coburn, C.A., Steele, T.G., et al. Structure-based design of potent and selective cell-permeable inhibitors of human ß-secretase (BACE-1). Journal of Medicinal Chemistry 47(26), 6447-6450 (2004). |
