For research use only. Not for therapeutic Use.
VSWRAPTA (Viral Suppressor of RNA-associated Protein Translation Activator)（Cat No.:I038125）is a protein involved in regulating the translation process of viral RNA within host cells. It is known to be a viral factor that aids in the suppression of host immune responses, thereby promoting viral replication and persistence. By interacting with host cellular machinery, VSWRAPTA can alter protein synthesis and translation regulation. Research on VSWRAPTA focuses on understanding its mechanisms of immune evasion and its potential as a target for antiviral therapies, particularly in the context of chronic viral infections.
| Catalog Number | I038125 |
| CAS Number | 2229829-30-3 |
| Synonyms | VSWRAPTA |
| Molecular Formula | C40H62N12O11 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | (2S)-2-[[(2S,3R)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxybutanoyl]amino]propanoic acid |
| InChI | InChI=1S/C40H62N12O11/c1-19(2)30(41)36(59)50-28(18-53)34(57)49-27(16-23-17-45-25-11-7-6-10-24(23)25)33(56)48-26(12-8-14-44-40(42)43)32(55)46-20(3)38(61)52-15-9-13-29(52)35(58)51-31(22(5)54)37(60)47-21(4)39(62)63/h6-7,10-11,17,19-22,26-31,45,53-54H,8-9,12-16,18,41H2,1-5H3,(H,46,55)(H,47,60)(H,48,56)(H,49,57)(H,50,59)(H,51,58)(H,62,63)(H4,42,43,44)/t20-,21-,22+,26-,27-,28-,29-,30-,31-/m0/s1 |
| InChIKey | DLKFGZCPOUJHBL-MWJQDZEGSA-N |
| SMILES | C[C@H]([C@@H](C(=O)N[C@@H](C)C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)[C@H](CO)NC(=O)[C@H](C(C)C)N)O |
| Reference | 1: Jarocki M, Sallouh O, Weberskirch R, Faissner A. The Tenascin-C-Derived Peptide VSWRAPTA Promotes Neuronal Branching Via Transcellular Activation of the Focal Adhesion Kinase (FAK) and the ERK1/2 Signaling Pathway In Vitro. Mol Neurobiol. 2018 May 18. doi: 10.1007/s12035-018-1108-7. [Epub ahead of print] PubMed PMID: 29777374. |
