For research use only. Not for therapeutic Use.
VSWRAPTA is a promoter of neuronal branching via transcellular activation of the focal adhesion kinase (FAK) and the ERK1/2 signaling pathway in vitro.
| Catalog Number | I038125 |
| CAS Number | 2229829-30-3 |
| Synonyms | VSWRAPTA |
| Molecular Formula | C40H62N12O11 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | Val-Ser-Trp-Arg-Ala-Pro-Thr-Ala |
| InChI | InChI=1S/C40H62N12O11/c1-19(2)30(41)36(59)50-28(18-53)34(57)49-27(16-23-17-45-25-11-7-6-10-24(23)25)33(56)48-26(12-8-14-44-40(42)43)32(55)46-20(3)38(61)52-15-9-13-29(52)35(58)51-31(22(5)54)37(60)47-21(4)39(62)63/h6-7,10-11,17,19-22,26-31,45,53-54H,8-9,12-16,18,41H2,1-5H3,(H,46,55)(H,47,60)(H,48,56)(H,49,57)(H,50,59)(H,51,58)(H,62,63)(H4,42,43,44)/t20-,21-,22+,26-,27-,28-,29-,30-,31-/m0/s1 |
| InChIKey | DLKFGZCPOUJHBL-MWJQDZEGSA-N |
| SMILES | O=C(N[C@@H](CO)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N3[C@@H](CCC3)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N |
| Reference | 1: Jarocki M, Sallouh O, Weberskirch R, Faissner A. The Tenascin-C-Derived Peptide VSWRAPTA Promotes Neuronal Branching Via Transcellular Activation of the Focal Adhesion Kinase (FAK) and the ERK1/2 Signaling Pathway In Vitro. Mol Neurobiol. 2018 May 18. doi: 10.1007/s12035-018-1108-7. [Epub ahead of print] PubMed PMID: 29777374. |
