VT101 free base

• CAT Number: I038126
• CAS Number: 65194-64-1
• Molecular Formula: C14H20N2O4S
• Molecular Weight: 312.38
• Purity: 98%
• Synonyms: VT101; VT-101; VT 101
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: methyl 2-(cyclohexylamino)-5-sulfamoylbenzoate
• InChI: InChI=1S/C14H20N2O4S/c1-20-14(17)12-9-11(21(15,18)19)7-8-13(12)16-10-5-3-2-4-6-10/h7-10,16H,2-6H2,1H3,(H2,15,18,19)
• InChIKey: CCFPLJFSHRAQPV-UHFFFAOYSA-N
• SMILES: COC(=O)C1=C(C=CC(=C1)S(=O)(=O)N)NC2CCCCC2

VT101 free base（Cat No.:I038126）is a small molecule compound that acts as a selective antagonist of the neurokinin 1 (NK1) receptor, which is involved in the regulation of pain, inflammation, and stress responses. By blocking the NK1 receptor, VT101 has potential therapeutic applications in treating conditions like chronic pain, anxiety, depression, and nausea, particularly in cancer patients undergoing chemotherapy. Preclinical studies suggest that it could offer a safer alternative to traditional treatments by reducing side effects. Further research and clinical trials are needed to assess its efficacy and safety profile in human patients.