VU 0155041 sodium salt

• CAT Number: I010738
• CAS Number: 1259372-69-4
• Molecular Formula: C14H14Cl2NNaO3
• Molecular Weight: 338.16
• Purity: ≥95%
• Synonyms: cis-2-[[(3,5-Dichlorophenyl)amino]carbonyl]cyclohexanecarboxylic acid sodium salt
• Target: Neuronal Signaling
• Solubility: Soluble to 25 mM in water
• Storage: Desiccate at RT
• SMILES: ClC1=CC(Cl)=CC(NC([C@@H]2[C@H](C([O-])=O)CCCC2)=O)=C1.[Na+]

Potent, positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50 = 798 and 693 nM at human and rat mGlu4 receptors respectively). Active in in vivo models of Parkinson/’s disease following i.c.v. administration.