For research use only. Not for therapeutic Use.
VU0155094 is a positive allosteric modulator with differential activity at the various group III mGluRs[1].
| Catalog Number | I012400 |
| CAS Number | 731006-86-3 |
| Synonyms | methyl 4-[3-[2-(4-acetamidophenyl)sulfanylacetyl]-2,5-dimethylpyrrol-1-yl]benzoate |
| Molecular Formula | C24H24N2O4S |
| Purity | ≥95% |
| InChI | InChI=1S/C24H24N2O4S/c1-15-13-22(16(2)26(15)20-9-5-18(6-10-20)24(29)30-4)23(28)14-31-21-11-7-19(8-12-21)25-17(3)27/h5-13H,14H2,1-4H3,(H,25,27) |
| InChIKey | BCNKQXDDMIBITO-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(N1C2=CC=C(C=C2)C(=O)OC)C)C(=O)CSC3=CC=C(C=C3)NC(=O)C |
| Reference | [1]. Jalan-Sakrikar N, et al. Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7. ACS Chem Neurosci. 2014 Dec 17;5(12):1221-37. |
