VU0420373

• CAT Number: I012124
• CAS Number: 38376-29-3
• Molecular Formula: C₁₅H₁₁FN₂O
• Molecular Weight: 254.26
• Purity: ≥95%
• Synonyms: 2-[5-(2-Fluorophenyl)-1H-pyrazol-3-yl]-phenol
• Target: Bacterial
• Storage: 2-8°C
• IUPAC Name: 2-[5-(2-fluorophenyl)-1H-pyrazol-3-yl]phenol
• InChI: InChI=1S/C15H11FN2O/c16-12-7-3-1-5-10(12)13-9-14(18-17-13)11-6-2-4-8-15(11)19/h1-9,19H,(H,17,18)
• InChIKey: SJPGLKXXUIEFLO-UHFFFAOYSA-N
• SMILES: C1=CC=C(C(=C1)C2=NNC(=C2)C3=CC=CC=C3F)O

VU0420373（Cat No.:I012124）is a research compound identified as a selective positive allosteric modulator (PAM) for the mGlu5 receptor, a subtype of metabotropic glutamate receptor in the brain. This receptor plays a significant role in regulating neurotransmission, making VU0420373 valuable in studying potential treatments for neurological disorders like schizophrenia, depression, and cognitive impairment. By enhancing mGlu5 receptor activity, VU0420373 may help restore balance in glutamate signaling, which is often disrupted in these conditions. Its selectivity and potency make it a promising candidate in preclinical research for targeted therapies in mental health.