For research use only. Not for therapeutic Use.
VU6028418（Cat No.:I043453）is a selective and potent inhibitor of the GPR40 receptor, a G protein-coupled receptor involved in regulating insulin secretion and glucose metabolism. By targeting GPR40, VU6028418 has shown potential in enhancing insulin sensitivity and improving glucose homeostasis, making it a promising candidate for treating type 2 diabetes and metabolic disorders. Preclinical studies have indicated its ability to modulate insulin release in response to glucose, offering a targeted approach to managing hyperglycemia. Ongoing research is focused on exploring its efficacy, safety, and potential for clinical use in metabolic disease treatment.
| CAS Number | 2649803-05-2 |
| Synonyms | (3aR,6aS)-2-(oxan-4-ylmethyl)-N-[6-(2,3,5-trifluorophenyl)pyridazin-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-amine |
| Molecular Formula | C23H27F3N4O |
| Purity | ≥95% |
| IUPAC Name | (3aR,6aS)-2-(oxan-4-ylmethyl)-N-[6-(2,3,5-trifluorophenyl)pyridazin-3-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-amine |
| InChI | InChI=1S/C23H27F3N4O/c24-17-9-19(23(26)20(25)10-17)21-1-2-22(29-28-21)27-18-7-15-12-30(13-16(15)8-18)11-14-3-5-31-6-4-14/h1-2,9-10,14-16,18H,3-8,11-13H2,(H,27,29)/t15-,16+,18? |
| InChIKey | ITSKPCHXUYILTR-BYICEURKSA-N |
| SMILES | C1COCCC1CN2C[C@H]3CC(C[C@H]3C2)NC4=NN=C(C=C4)C5=C(C(=CC(=C5)F)F)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
