For research use only. Not for therapeutic Use.
VUF-5574 is a selective antagonist of adenosine A3 receptor with a Ki of 4.03 nM for the recombinant human receptor[1].
| Catalog Number | I010397 |
| CAS Number | 280570-45-8 |
| Synonyms | 1-(2-methoxyphenyl)-3-(2-pyridin-3-ylquinazolin-4-yl)urea |
| Molecular Formula | C21H17N5O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H17N5O2/c1-28-18-11-5-4-10-17(18)24-21(27)26-20-15-8-2-3-9-16(15)23-19(25-20)14-7-6-12-22-13-14/h2-13H,1H3,(H2,23,24,25,26,27) |
| InChIKey | YRAFEJSZTVWUMD-UHFFFAOYSA-N |
| SMILES | COC1=CC=CC=C1NC(=O)NC2=NC(=NC3=CC=CC=C32)C4=CN=CC=C4 |
| Reference | [1]. van Muijlwijk-Koezen JE, et al. Isoquinoline and quinazoline urea analogues as antagonists for the human adenosine A(3) receptor. J Med Chem. 2000 Jun 1;43(11):2227-38. |
