VY-3-135

• CAT Number: I043701
• CAS Number: 1824637-41-3
• Molecular Formula: C26H27N3O3
• Molecular Weight: 429.51
• Purity: ≥95%
• Synonyms: 3-ethyl-2-[hydroxy(diphenyl)methyl]-N-[(2R)-2-hydroxypropyl]benzimidazole-5-carboxamide
• InChI: InChI=1S/C26H27N3O3/c1-3-29-23-16-19(24(31)27-17-18(2)30)14-15-22(23)28-25(29)26(32,20-10-6-4-7-11-20)21-12-8-5-9-13-21/h4-16,18,30,32H,3,17H2,1-2H3,(H,27,31)/t18-/m1/s1
• InChIKey: KTPYOTKTDCLZHR-GOSISDBHSA-N
• SMILES: CCN1C2=C(C=CC(=C2)C(=O)NC[C@@H](C)O)N=C1C(C3=CC=CC=C3)(C4=CC=CC=C4)O

VY-3-135（Cat No.:I043701）is a selective small molecule inhibitor that targets the protein PAK4 (p21-activated kinase 4), a serine/threonine kinase involved in regulating cellular processes such as cell migration, survival, and cytoskeletal dynamics. By inhibiting PAK4, VY-3-135 disrupts critical signaling pathways that are often upregulated in cancer cells, leading to reduced tumor growth, migration, and metastasis. Preclinical studies have shown that VY-3-135 may have therapeutic potential in treating various cancers, particularly those with PAK4 overexpression. This compound represents a promising approach for targeting oncogenic signaling in cancer therapy.