For research use only. Not for therapeutic Use.
VYN-00381 is a Novel Potent and Selective Inducible Nitric Oxide Synthase (iNOS) Inhibitor (IC50 = 74 nM) with high BBB permeability (Pe = 19.1 × 10-6 cm/s) for Parkinson's Disease. This product has no formal name. For the convenience of scientific communication, we named it by combining its InChi Key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming).
| Catalog Number | I038226 |
| Synonyms | VYN-00381; VYN00381; VYN 00381; iNOS-IN-18; |
| Molecular Formula | C19H15F4NO3 |
| Purity | 98% |
| Solubility | To be determined |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | (S,E)-3-(4-fluorophenyl)-2-(3-(4-(trifluoromethyl)phenyl)acrylamido)propanoic acid |
| InChI | InChI=1S/C19H15F4NO3/c20-15-8-3-13(4-9-15)11-16(18(26)27)24-17(25)10-5-12-1-6-14(7-2-12)19(21,22)23/h1-10,16H,11H2,(H,24,25)(H,26,27)/b10-5+/t16-/m0/s1 |
| InChIKey | VXTNIOWCDILANK-YKXBDCQTSA-N |
| SMILES | O=C(O)[C@@H](NC(/C=C/C1=CC=C(C(F)(F)F)C=C1)=O)CC2=CC=C(F)C=C2 |
