VZN-80448

• CAT Number: I038229
• CAS Number: 62480-44-8
• Molecular Formula: C16H21ClN2O3
• Molecular Weight: 324.81
• Purity: 98%
• Synonyms: VZN-80448; VZN 80448; VZN80448; L-Leu-AMC HCl; L-Leu-AMC hydrochloride
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: (S)-2-amino-4-methyl-N-(4-methyl-2-oxo-2H-chromen-7-yl)pentanamide hydrochloride
• InChI: InChI=1S/C16H20N2O3.ClH/c1-9(2)6-13(17)16(20)18-11-4-5-12-10(3)7-15(19)21-14(12)8-11;/h4-5,7-9,13H,6,17H2,1-3H3,(H,18,20);1H/t13-;/m0./s1
• InChIKey: VCRXITKKWBOQRZ-ZOWNYOTGSA-N
• SMILES: CC(C1=CC=C(C=C1O2)NC([C@H](CC(C)C)N)=O)=CC2=O.Cl

VZN-80448 (Cat No.: I038229) is a potent and selective inhibitor designed for neurological and metabolic disease research. It modulates key signaling pathways involved in neurodegeneration, cellular metabolism, and inflammatory responses. With high specificity and bioavailability, VZN-80448 is a valuable tool for studying neuroprotective mechanisms, metabolic disorders, and related therapeutic targets. Researchers use it to explore potential treatments for conditions such as Alzheimer’s disease, Parkinson’s disease, and metabolic syndrome. Its stability and efficacy ensure reliable experimental outcomes in drug discovery and biomedical research.

Reference

1: Cheng T, Chepkirui C, Decock C, Matasyoh JC, Stadler M. Skeletocutins M-Q: biologically active compounds from the fruiting bodies of the basidiomycete Skeletocutis sp. collected in Africa. Beilstein J Org Chem. 2019 Nov 19;15:2782-2789. doi: 10.3762/bjoc.15.270. PMID: 31807212; PMCID: PMC6880814.