WAAG-3R TFA

For research use only. Not for therapeutic Use.

  • CAT Number: I040098
  • Molecular Formula: C69H109N23O24.xC2HF3O2
  • Molecular Weight: 1644.74 (free base)
  • Purity: ≥95%
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WAAG-3R TFA is a biological active peptide. (Aggrecanases belong to the ADAMTS (A disintegrin and metalloprotease with thrombospondin motif) family of proteases. Aggrecanases cleave aggrecan, the major structural component of cartilage. Aggrecanase-1 (ADAMTS-4) is a major aggrecanase in human osteoarthritic cartilage. This FRET peptide was used in an ADAMTS-4 (Aggrecanase-1) assay. Ex/Em = 340/420 nm.)[1].


Catalog Number I040098
Molecular Formula C69H109N23O24.xC2HF3O2
Purity ≥95%
Reference

[1]. De Savi C, et al. The design and synthesis of novel N-hydroxyformamide inhibitors of ADAM-TS4 for the treatment of osteoarthritis[J]. Bioorganic & medicinal chemistry letters, 2011, 21(5): 1376-1381.
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