For research use only. Not for therapeutic Use.
WAY 316606 hydrochloride (CAT: I011023) is a small molecule inhibitor of Secreted Frizzled-Related Protein-1 (sFRP-1), a negative regulator of the Wnt signaling pathway. By inhibiting the interaction between sFRP-1 and Wnt, WAY 316606 hydrochloride enhances Wnt signaling, which plays a crucial role in various biological processes, including bone formation. In a murine calvarial organ culture assay, this compound has been shown to increase total bone area, suggesting its potential as a modulator of bone development and regeneration. The inhibition of sFRP-1 by WAY 316606 hydrochloride may have implications in the field of regenerative medicine and bone-related disorders.
| Catalog Number | I011023 |
| CAS Number | 1781835-02-6 |
| Synonyms | 5-(Phenylsulfonyl)-N-4-piperidinyl-2-(trifluoromethyl)benzene sulfonamide hydrochloride |
| Molecular Formula | C18H19F3N2O4S2.HCl |
| Purity | ≥95% |
| Target | sFRP-1 |
| Solubility | Soluble to 20 mM in DMSO |
| Storage | Store at +4C |
| Related CAS | 915759-45-4 |
