For research use only. Not for therapeutic Use.
WE 1073 (Cat No.: I038271) is a selective inhibitor of dopamine β-hydroxylase (DBH), the enzyme responsible for converting dopamine to norepinephrine. By blocking this conversion, WE 1073 decreases norepinephrine levels while increasing dopamine concentrations, making it a valuable tool in neurochemical and pharmacological studies. It is used to investigate the role of catecholamines in stress, mood regulation, and cardiovascular function. WE 1073 is particularly useful in research on neuropsychiatric disorders, including depression and anxiety, where dysregulated catecholamine balance plays a critical role.
| CAS Number | 88986-12-3 |
| Synonyms | WE 1073; WE-1073; WE1073. |
| Molecular Formula | C15H10BrClN4O2S |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | WE 1073 |
| InChI | InChI=1S/C15H10BrClN4O2S/c16-10-5-8-12(7-3-1-2-4-9(7)17)18-14(23)13-20-19-11(6-22)21(13)15(8)24-10/h1-5,14,22-23H,6H2/t14-/m0/s1 |
| InChIKey | BWIRZXDLEWQDEN-AWEZNQCLSA-N |
| SMILES | n12c([C@@H](N=C(c3c1sc(c3)Br)c1c(cccc1)Cl)O)nnc2CO |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
