WEE1-IN-4

• CAT Number: I012112
• CAS Number: 622855-37-2
• Molecular Formula: C20H11ClN2O3
• Molecular Weight: 362.77
• Purity: ≥95%
• Synonyms: 4-(2-chlorophenyl)-9-hydroxy-6H-pyrrolo[3,4-c]carbazole-1,3-dione
• InChI: InChI=1S/C20H11ClN2O3/c21-13-4-2-1-3-10(13)11-8-15-16(18-17(11)19(25)23-20(18)26)12-7-9(24)5-6-14(12)22-15/h1-8,22,24H,(H,23,25,26)
• InChIKey: DPEXRCOBPACFOO-UHFFFAOYSA-N
• SMILES: C1=CC=C(C(=C1)C2=CC3=C(C4=C(N3)C=CC(=C4)O)C5=C2C(=O)NC5=O)Cl

WEE1-IN-4 is a potent checkpoint Wee1 kinase inhibitor with an IC50 of 0.011 μM[1].

Reference

[1]. Kanin Wichapong, et al. Receptor-based 3D-QSAR studies of checkpoint Wee1 kinase inhibitors. Eur J Med Chem. 2009 Apr;44(4):1383-95.
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