For research use only. Not for therapeutic Use.
WH-4-025 is a Salt-inducible kinase (SIK) inhibitor (WO2016023014 A2)[1].
| Catalog Number | I044650 |
| CAS Number | 1876463-35-2 |
| Synonyms | [2-methyl-5-[[3-(trifluoromethyl)phenyl]carbamoyl]phenyl] N-(2,4-dimethoxyphenyl)-N-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]carbamate |
| Molecular Formula | C39H38F3N7O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C39H38F3N7O5/c1-25-8-9-26(36(50)44-29-7-5-6-27(23-29)39(40,41)42)22-33(25)54-38(51)49(32-15-14-31(52-3)24-34(32)53-4)35-16-17-43-37(46-35)45-28-10-12-30(13-11-28)48-20-18-47(2)19-21-48/h5-17,22-24H,18-21H2,1-4H3,(H,44,50)(H,43,45,46) |
| InChIKey | MWWDOHSKUDECFQ-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)OC(=O)N(C3=C(C=C(C=C3)OC)OC)C4=NC(=NC=C4)NC5=CC=C(C=C5)N6CCN(CC6)C |
| Reference | [1]. Brookline Avenue, et al. USES OF SALT-INDUCIBLE KINASE (SIK) INHIBITORS. Patent WO2016023014A2. |
