WM 3835

• CAT Number: I038309
• CAS Number: 2229025-70-9
• Molecular Formula: C20H17FN2O4S
• Molecular Weight: 400.42
• Purity: 98%
• Synonyms: WM 3835; WM3835; WM-3835
• Target: Apoptosis
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: 4°C, protect from light
• IUPAC Name: 2-fluoro-N'-(3-hydroxyphenyl)sulfonyl-3-methyl-5-phenylbenzohydrazide
• InChI: InChI=1S/C20H17FN2O4S/c1-13-10-15(14-6-3-2-4-7-14)11-18(19(13)21)20(25)22-23-28(26,27)17-9-5-8-16(24)12-17/h2-12,23-24H,1H3,(H,22,25)
• InChIKey: KVJFJJXCBRSCDY-UHFFFAOYSA-N
• SMILES: CC1=CC(=CC(=C1F)C(=O)NNS(=O)(=O)C2=CC=CC(=C2)O)C3=CC=CC=C3

WM-3835（Cat No.:I038309）is a potent and selective inhibitor of lactate dehydrogenase A (LDHA), a key enzyme involved in the conversion of pyruvate to lactate during glycolysis. By inhibiting LDHA, WM-3835 disrupts cancer cell metabolism, particularly in tumors that rely on glycolysis for energy production, commonly known as the Warburg effect. This compound has demonstrated anti-tumor activity in preclinical studies, making it a valuable tool for cancer research targeting metabolic vulnerabilities. WM-3835 holds potential for therapeutic development in cancers driven by altered metabolic pathways.