For research use only. Not for therapeutic Use.
Wnt pathway inhibitor 4 (compound 16D) is an anticancer agent that has anti-proliferative activity[1].
Wnt pathway inhibitor 4 (Compound 16D) (72 h) inhibits proliferation of human A375 melanoma cells (IC50: 23.3 nM)[1].
| Catalog Number | I041076 |
| CAS Number | 663214-57-1 |
| Synonyms | 6-amino-8-(3-bromo-4,5-dimethoxyphenyl)-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile |
| Molecular Formula | C19H15BrN2O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C19H15BrN2O5/c1-23-16-4-9(3-12(20)18(16)24-2)17-10-5-14-15(26-8-25-14)6-13(10)27-19(22)11(17)7-21/h3-6,17H,8,22H2,1-2H3 |
| InChIKey | NJNZVKZFRYVFSS-UHFFFAOYSA-N |
| SMILES | COC1=C(C(=CC(=C1)C2C3=CC4=C(C=C3OC(=C2C#N)N)OCO4)Br)OC |
| Reference | [1]. Zhang H, et al. Design, synthesis and characterization of potent microtubule inhibitors with dual anti-proliferative and anti-angiogenic activities. Eur J Med Chem. 2018 Sep 5;157:380-396. |
