For research use only. Not for therapeutic Use.
WRN inhibitor 3 (example 110), a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor. WRN inhibitor 3 can be used for the research of cancer[1].
| Catalog Number | I040875 |
| CAS Number | 2923009-48-5 |
| Synonyms | 6-[2-(cyclopropylmethoxy)phenyl]-N-[(3R)-1,1-dioxo-2,3-dihydrothiophen-3-yl]-2-oxo-1H-pyridine-3-carboxamide |
| Molecular Formula | C20H20N2O5S |
| Purity | ≥95% |
| InChI | InChI=1S/C20H20N2O5S/c23-19(21-14-9-10-28(25,26)12-14)16-7-8-17(22-20(16)24)15-3-1-2-4-18(15)27-11-13-5-6-13/h1-4,7-10,13-14H,5-6,11-12H2,(H,21,23)(H,22,24)/t14-/m1/s1 |
| InChIKey | OCAWWHPFNVVCII-CQSZACIVSA-N |
| SMILES | C1CC1COC2=CC=CC=C2C3=CC=C(C(=O)N3)C(=O)NC4CS(=O)(=O)C=C4 |
| Reference | [1]. Ashley ADAMS, et al. Cyclic vinyl sulfone compounds as wrn inhibitors. Patent. WO2023062575 A1. |
