WRN inhibitor 4

For research use only. Not for therapeutic Use.

  • CAT Number: I040874
  • CAS Number: 2923009-45-2
  • Molecular Formula: C16H14N2O5S
  • Molecular Weight: 346.36
  • Purity: ≥95%
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WRN Inhibitor 4(CAT: I040874) is a small molecule inhibitor that targets the Werner syndrome protein (WRN), a helicase involved in DNA repair and maintaining genomic stability. WRN plays a crucial role in the repair of DNA damage, and its dysfunction is linked to premature aging and genomic instability. By inhibiting WRN, this compound disrupts the repair of DNA double-strand breaks and inhibits the growth of cancer cells with defective DNA repair mechanisms. WRN Inhibitor 4 is being studied in Cancer Disease Research for its potential to enhance the efficacy of chemotherapy and radiation therapy by sensitizing tumors with deficient DNA repair pathways.


CAS Number 2923009-45-2
Synonyms

N-[(3R)-1,1-dioxo-2,3-dihydrothiophen-3-yl]-5-hydroxy-2-oxo-6-phenyl-1H-pyridine-3-carboxamide

Molecular Formula C16H14N2O5S
Purity ≥95%
IUPAC Name N-[(3R)-1,1-dioxo-2,3-dihydrothiophen-3-yl]-5-hydroxy-2-oxo-6-phenyl-1H-pyridine-3-carboxamide
InChI InChI=1S/C16H14N2O5S/c19-13-8-12(15(20)17-11-6-7-24(22,23)9-11)16(21)18-14(13)10-4-2-1-3-5-10/h1-8,11,19H,9H2,(H,17,20)(H,18,21)/t11-/m1/s1
InChIKey HFIIQCVNTGZNPC-LLVKDONJSA-N
SMILES C1[C@@H](C=CS1(=O)=O)NC(=O)C2=CC(=C(NC2=O)C3=CC=CC=C3)O

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