For research use only. Not for therapeutic Use.
WWL-154(CAT: I038358) is a serine hydrolase inhibitor. Serine hydrolases are a large and diverse group of enzymes that play crucial roles in various physiological processes in mammals. They are involved in numerous cellular functions and are targeted by drugs for the treatment of various diseases, including diabetes, obesity, and neurodegenerative disorders. WWL-154 acts as an inhibitor of serine hydrolases, potentially modulating their activity and providing opportunities for therapeutic intervention.
| Catalog Number | I038358 |
| CAS Number | 1338574-93-8 |
| Synonyms | WWL-154; WWL 154; WWL154; |
| Molecular Formula | C18H19N3O5 |
| Purity | 98% |
| Target | Neuronal Signaling |
| Solubility | To be determined |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 4-(4-Methoxyphenyl)-1-piperazinecarboxylic acid, 4-nitrophenyl ester |
| InChI | InChI=1S/C18H19N3O5/c1-25-16-6-2-14(3-7-16)19-10-12-20(13-11-19)18(22)26-17-8-4-15(5-9-17)21(23)24/h2-9H,10-13H2,1H3 |
| InChIKey | TULVXRNEEQWFGU-UHFFFAOYSA-N |
| SMILES | O=C(N1CCN(C2=CC=C(OC)C=C2)CC1)OC3=CC=C([N+]([O-])=O)C=C3 |
| Reference | Bachovchin DA, Ji T, Li W, Simon GM, Blankman JL, Adibekian A, Hoover H, Niessen S, Cravatt BF. Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening. Proc Natl Acad Sci U S A. 2010 Dec 7;107(49):20941-6. doi: 10.1073/pnas.1011663107. Epub 2010 Nov 17. PMID: 21084632; PMCID: PMC3000285. |
