For research use only. Not for therapeutic Use.
WWL229 is a selective inhibitor of carboxylesterase 3 (Ces3) with an IC50 of 1.94 µM. WWL229 promotes lipid storage in cultured adipocytes and prevents basal lipolysis[1].
| Catalog Number | R024470 |
| CAS Number | 1338575-28-2 |
| Synonyms | (4-nitrophenyl) 2-(3-methoxypropyl)piperidine-1-carboxylate |
| Molecular Formula | C16H22N2O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C16H22N2O5/c1-22-12-4-6-13-5-2-3-11-17(13)16(19)23-15-9-7-14(8-10-15)18(20)21/h7-10,13H,2-6,11-12H2,1H3 |
| InChIKey | XVBRVSAGMWRVCK-UHFFFAOYSA-N |
| SMILES | COCCCC1CCCCN1C(=O)OC2=CC=C(C=C2)[N+](=O)[O-] |
| Reference | [1]. Dominguez E, et al. Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes. Nat Chem Biol. 2014 Feb;10(2):113-21. |
