For research use only. Not for therapeutic Use.
WZ8040 (Cat.No:I000802) is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).
| Catalog Number | I000802 |
| CAS Number | 1214265-57-2 |
| Synonyms | N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide |
| Molecular Formula | C24H25ClN6OS |
| Purity | ≥95% |
| Target | Protein Tyrosine Kinase/RTK |
| Solubility | DMSO ≥93mg/mL Water <1.2mg/mL Ethanol ≥2.8mg/mL |
| Storage | 3 years -20℃ powder |
| IUPAC Name | N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]sulfanylphenyl]prop-2-enamide |
| InChI | InChI=1S/C24H25ClN6OS/c1-3-22(32)27-18-5-4-6-20(15-18)33-23-21(25)16-26-24(29-23)28-17-7-9-19(10-8-17)31-13-11-30(2)12-14-31/h3-10,15-16H,1,11-14H2,2H3,(H,27,32)(H,26,28,29) |
| InChIKey | KIISCIGBPUVZBF-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)SC4=CC=CC(=C4)NC(=O)C=C)Cl |
| Reference | <p style=/line-height:25px/> |
