Xamoterol hemifumarate

• CAT Number: I010338
• CAS Number: 73210-73-8
• Molecular Formula: C16H25N3O5.0.5C4H4O4
• Molecular Weight: 397.43
• Purity: ≥95%
• Synonyms: Alternative Name: ICI 118,587
• Target: Neuronal Signaling
• Solubility: Soluble to 50 mM in water and to 100 mM in DMSO
• Storage: Store at RT
• IUPAC Name: (E)-but-2-enedioic acid;N-[2-[[2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]morpholine-4-carboxamide
• InChI: InChI=1S/2C16H25N3O5.C4H4O4/c2*20-13-1-3-15(4-2-13)24-12-14(21)11-17-5-6-18-16(22)19-7-9-23-10-8-19;5-3(6)1-2-4(7)8/h2*1-4,14,17,20-21H,5-12H2,(H,18,22);1-2H,(H,5,6)(H,7,8)/b;;2-1+
• InChIKey: QEDVGROSOZBGOZ-WXXKFALUSA-N
• SMILES: C1COCCN1C(=O)NCCNCC(COC2=CC=C(C=C2)O)O.C1COCCN1C(=O)NCCNCC(COC2=CC=C(C=C2)O)O.C(=C/C(=O)O)\C(=O)O

Xamoterol hemifumarate（Cat No.:I010338）is a beta-1 adrenergic agonist used in the treatment of heart failure and other cardiovascular conditions. It selectively stimulates beta-1 adrenergic receptors in the heart, increasing myocardial contractility and improving cardiac output without significantly affecting heart rate. This makes xamoterol useful for managing heart failure symptoms and improving exercise tolerance in patients with reduced heart function. As a positive inotropic agent, it enhances the heart’s pumping ability while minimizing side effects like arrhythmias, commonly seen with non-selective beta-agonists. Ongoing research continues to explore its full clinical potential.