For research use only. Not for therapeutic Use.
Xanthoangelol (Cat.No:I017903) is a flavonoid compound found in Angelica keiskei, a plant traditionally used in East Asian medicine. It exhibits various bioactive properties, including antioxidant, anti-inflammatory, and anticancer effects. Studies suggest that xanthoangelol may help modulate cellular signaling pathways involved in inflammation and cancer progression, potentially inhibiting tumor growth and metastasis. Its ability to protect against oxidative stress further supports its potential in treating conditions related to chronic inflammation and cancer. Ongoing research is exploring its therapeutic applications.
| Catalog Number | I017903 |
| CAS Number | 62949-76-2 |
| Molecular Formula | C₂₅H₂₈O₄ |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| IUPAC Name | (E)-1-[3-[(2E)-3,7-dimethylocta-2,6-dienyl]-2,4-dihydroxyphenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one |
| InChI | 1S/C25H28O4/c1-17(2)5-4-6-18(3)7-13-21-24(28)16-14-22(25(21)29)23(27)15-10-19-8-11-20(26)12-9-19/h5,7-12,14-16,26,28-29H,4,6,13H2,1-3H3/b15-10+,18-7+ |
| InChIKey | LRSMBOSQWGHYCW-MDGZPELGSA-N |
| SMILES | CC(=CCC/C(=C/CC1=C(C=CC(=C1O)C(=O)/C=C/C2=CC=C(C=C2)O)O)/C)C |
| Reference | [1]. Li Y, et al. Xanthoangelol and 4-hydroxyderrcin suppress obesity-induced inflammatory responses. Obesity (Silver Spring). 2016 Nov;24(11):2351-2360.<br>[2]. Inamori Y, et al. Antibacterial activity of two chalcones, xanthoangelol and 4-hydroxyderricin, isolated from the root of Angelica keiskei KOIDZUMI. Chem Pharm Bull (Tokyo). 1991 Jun;39(6):1604-5.<br>[3]. Kim JH, et al. Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K. Biomol Ther (Seoul). 2013 May 30;21(3):234-40.<br>[4]. Keiichi TABATA, et al. Xanthoangelol, a Major Chalcone Constituent of Angelica keiskei, Induces Apoptosis in Neuroblastoma and Leukemia Cells. Biol. Pharm. Bull. 28(8) 1404-1407 (2005). |
