For research use only. Not for therapeutic Use.
XLR11 (Item No. <span class=/itemid/>11565</span>) is a synthetic cannabinoid (CB) featuring a tetramethylcyclopropyl group, which reportedly confers selectivity for the peripheral CB<sub>2</sub> receptor over the central CB<sub>1</sub> receptor. XLR11 also has an N-<wbr></wbr>(5-<wbr></wbr>fluoropentyl) chain, which increases binding to both CB receptors. XLR11 N-<wbr></wbr>(4-<wbr></wbr>pentenyl) analog is a variant of XLR11 which replaces the N-<wbr></wbr>(5-<wbr></wbr>fluoropentyl) chain with N-<wbr></wbr>(4-<wbr></wbr>pentenyl). This analog is a commonly observed component of herbal mixtures (Spice/K<sub>2</sub>) containing synthetic CBs with the 5-<wbr></wbr>fluoropentyl moiety, like XLR11, AM2201 (Item No. <span class=/itemid/>10707</span>), and MAM2201 (Item No. <span class=/itemid/>9001219</span>). The biological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.
| Catalog Number | R060810 |
| CAS Number | 1445578-20-0 |
| Synonyms | UR-144 N-(4-pentenyl) analog |
| Molecular Formula | C21H27NO |
| Purity | ≥95% |
| Storage | -20°C |
| InChI | InChI=1S/C21H27NO/c1-6-7-10-13-22-14-16(15-11-8-9-12-17(15)22)18(23)19-20(2,3)21(19,4)5/h6,8-9,11-12,14,19H,1,7,10,13H2,2-5H3 |
| InChIKey | NXTLUQFOTQPMOD-UHFFFAOYSA-N |
| SMILES | O=C(C1C(C)(C)C1(C)C)C2=CN(CCCC=C)C3=C2C=CC=C3 |
| Reference | 1.Frost, J.M.,Dart, M.J.,Tietje, K.R., et al. Indol-3-ylcycloalkyl ketones: Effects of N1 substituted indole side chain variations on CB2 cannabinoid receptor activity. Journal of Medicinal Chemistry 53, 295-315 (2010). |
