XP-59

• CAT Number: I015463
• CAS Number: 890402-73-0
• Molecular Formula: C₁₅H₁₄N₄O₂
• Molecular Weight: 282.30
• Purity: ≥95%
• Target: SARS-CoV
• IUPAC Name: benzotriazol-1-yl 4-(dimethylamino)benzoate
• InChI: InChI=1S/C15H14N4O2/c1-18(2)12-9-7-11(8-10-12)15(20)21-19-14-6-4-3-5-13(14)16-17-19/h3-10H,1-2H3
• InChIKey: UOITWBIZHQLMTH-UHFFFAOYSA-N
• SMILES: CN(C)C1=CC=C(C=C1)C(=O)ON2C3=CC=CC=C3N=N2

XP-59（Cat No.:I015463）is a potent, selective small molecule inhibitor targeting the c-Myc oncoprotein, a key driver of tumorigenesis. By binding to c-Myc, XP-59 disrupts its interaction with other transcription factors and its function in regulating gene expression, effectively suppressing tumor cell proliferation. This makes it a promising candidate for cancer therapy, particularly for tumors driven by c-Myc overexpression. Preclinical studies indicate that XP-59 can inhibit tumor growth in a variety of cancer models, offering potential as a targeted treatment in precision oncology.

Reference

[1]. Verschueren KH, et al,. A structural view of the inactivation of the SARS coronavirus main proteinase by benzotriazole esters. Chem Biol. 2008 Jun;15(6):597-606.