Xylometazoline free base

• CAT Number: I038478
• CAS Number: 526-36-3
• Molecular Formula: C16H24N2
• Molecular Weight: 244.38
• Purity: 98%
• Synonyms: Xylometazoline free base, BA 11391; BA-11391; BA11391
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 1H-Imidazole, 2-((4-(1,1-dimethylethyl)-2,6-dimethylphenyl)methyl)-4,5-dihydro-
• InChI: InChI=1S/C16H24N2/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15/h8-9H,6-7,10H2,1-5H3,(H,17,18)
• InChIKey: HUCJFAOMUPXHDK-UHFFFAOYSA-N
• SMILES: CC1=C(CC2=NCCN2)C(C)=CC(C(C)(C)C)=C1

Xylometazoline, also spelled xylomethazoline, is a medication used to reduce symptoms of nasal congestion, allergic rhinitis, and sinusitis. Use is not recommended for more than seven days. Xylometazoline is an imidazole derivative which is designed to mimic the molecular shape of adrenaline. It binds to α1 and α2 adrenergic receptors in the nasal mucosa. Due to its sympathomimetic effects, it should not be used by people with high blood pressure, or other heart problems.

Reference

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