Y 26611

• CAT Number: I038515
• CAS Number: 143375-60-4
• Molecular Formula: C18H19F2N3O4
• Molecular Weight: 379.36
• Purity: 98%
• Synonyms: Y 26611; Y-26611; Y26611.
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 7-[2-(aminomethyl)morpholin-4-yl]-1-cyclopropyl-6,8-difluoro-4-oxoquinoline-3-carboxylic acid
• InChI: InChI=1S/C18H19F2N3O4/c19-13-5-11-15(14(20)16(13)22-3-4-27-10(6-21)7-22)23(9-1-2-9)8-12(17(11)24)18(25)26/h5,8-10H,1-4,6-7,21H2,(H,25,26)
• InChIKey: MVKGRIHKSLEKTE-UHFFFAOYSA-N
• SMILES: C1CC1N2C=C(C(=O)C3=CC(=C(C(=C32)F)N4CCOC(C4)CN)F)C(=O)O

Y 26611(CAT: I038515) is a potent and selective 5-lipoxygenase (5-LOX) inhibitor, targeting the enzyme responsible for the production of leukotrienes from arachidonic acid. By inhibiting leukotriene biosynthesis, Y 26611 demonstrates significant anti-inflammatory and anti-asthmatic properties. It is widely used in inflammation and respiratory disease research to study leukotriene-mediated pathways involved in conditions such as asthma, chronic obstructive pulmonary disease (COPD), and allergic reactions. Its specificity for 5-LOX makes Y 26611 a valuable tool for exploring the therapeutic potential of leukotriene pathway modulation in inflammatory disorders and for developing targeted treatments with fewer off-target effects.