YK-11

• CAT Number: I005882
• CAS Number: 1370003-76-1
• Molecular Formula: C25H34O6
• Molecular Weight: 430.54
• Purity: ≥95%
• Synonyms: YK-11; YK 11; YK11
• Target: Androgen Receptor
• Solubility: Soluble in DMSO
• Storage: Store at +4C
• IUPAC Name: methyl (2E)-2-[(8R,9S,10R,13S,14S,17S)-2/'-methoxy-2/',13-dimethyl-3-oxospiro[1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-17,5/'-1,3-dioxolane]-4/'-ylidene]acetate
• InChI: InChI=1S/C25H34O6/c1-23-11-9-18-17-8-6-16(26)13-15(17)5-7-19(18)20(23)10-12-25(23)21(14-22(27)28-3)30-24(2,29-4)31-25/h13-14,17-20H,5-12H2,1-4H3/b21-14+/t17-,18+,19+,20-,23-,24?,25+/m0/s1
• InChIKey: KCQHQCDHFVGNMK-PQUNLUOYSA-N
• SMILES: CC12CCC3C(C1CCC24C(=CC(=O)OC)OC(O4)(C)OC)CCC5=CC(=O)CCC35

YK-11(CAT: I005882) is a synthetic, steroidal selective androgen receptor modulator (SARM).YK-11 is a gene-selective partial agonist of the androgen receptor (AR) and does not induce the physical interaction between the NTD/AF1 and LBD/AF2 (known as the N/C interaction), which is required for full transactivation of the AR. The drug has anabolic activity in vitro in C2C12 myoblasts and shows greater potency than dihydrotestosterone (DHT) in this regard.