For research use only. Not for therapeutic Use.
YMU1 is a selective inhibitor of human thymidylate kinase (hTMPK) with an IC50 of 610 nM[1].
| Catalog Number | R067078 |
| CAS Number | 902589-96-2 |
| Synonyms | ethyl 4-[2-(4,6-dimethyl-3-oxo-[1,2]thiazolo[5,4-b]pyridin-2-yl)acetyl]piperazine-1-carboxylate |
| Molecular Formula | C17H22N4O4S |
| Purity | ≥95% |
| InChI | InChI=1S/C17H22N4O4S/c1-4-25-17(24)20-7-5-19(6-8-20)13(22)10-21-16(23)14-11(2)9-12(3)18-15(14)26-21/h9H,4-8,10H2,1-3H3 |
| InChIKey | XXUFNNVFZFVKGP-UHFFFAOYSA-N |
| SMILES | CCOC(=O)N1CCN(CC1)C(=O)CN2C(=O)C3=C(S2)N=C(C=C3C)C |
| Reference | [1]. Hu CM, et al. Tumor cells require thymidylate kinase to prevent dUTP incorporation during DNA repair. Cancer Cell. 2012 Jul 10;22(1):36-50. |
