Yohimbine Hydrochloride

• CAT Number: I004458
• CAS Number: 65-19-0
• Molecular Formula: C21H26N2O3 • HCl
• Molecular Weight: 390.91
• Purity: ≥95%
• Synonyms: NIH 9689;NSC 19509;Yohimbe
• Target: GPCR/G Protein
• Solubility: 10 mM in DMSO
• Storage: 3 years -20C powder
• IUPAC Name: methyl (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride
• InChI: InChI=1S/C21H26N2O3.ClH/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24;/h2-5,12,15,17-19,22,24H,6-11H2,1H3;1H/t12-,15-,17-,18-,19+;/m0./s1
• InChIKey: PIPZGJSEDRMUAW-VJDCAHTMSA-N
• SMILES: COC(=O)[C@H]1[C@H](CC[C@@H]2[C@@H]1C[C@H]3C4=C(CCN3C2)C5=CC=CC=C5N4)O.Cl

Yohimbine Hydrochloride(CAT: I004458) is a selective α2-adrenergic receptor antagonist widely used in pharmacological and physiological research. By blocking α2-adrenergic receptors, it enhances sympathetic outflow and increases the release of norepinephrine, making it a valuable tool for studying cardiovascular, metabolic, and central nervous system functions. Yohimbine Hydrochloride is also extensively researched for its potential applications in erectile dysfunction and as a probe for stress and anxiety-related disorders. Its high specificity and consistent bioactivity make it suitable for in vitro and in vivo studies, advancing therapeutic research in adrenergic signaling pathways and related conditions.