(Z)-2-(Methoxyimino)-3-oxo-butanoic Acid Ethyl Ester

• CAT Number: C000274
• CAS Number: 66340-86-1
• Molecular Formula: C₇H₁₁NO₄
• Molecular Weight: 173.17
• Purity: ≥95%
• Synonyms: (2Z)-2-(Methoxyimino)-3-oxo-butanoic Acid Ethyl Ester; Ethyl syn-2-Methoxyiminoacetoacetate
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• Appearance: Clear Colorless to Light Orange Oil
• Storage: 4°C, Inert atmosphere

(Z)-2-(Methoxyimino)-3-oxo-butanoic Acid Ethyl Ester (CAT: C000274) is a key intermediate in the synthesis of (E)-Cefodizime, a cephalosporin antibiotic. (E)-Cefodizime exhibits antimicrobial activity against a wide range of bacteria by interfering with their cell wall synthesis. The synthesis of (E)-Cefodizime involves strategic transformations of intermediate compounds, with (Z)-2-(Methoxyimino)-3-oxo-butanoic Acid Ethyl Ester serving as a critical building block. The use of this intermediate enables the production of (E)-Cefodizime, a valuable pharmaceutical compound used to combat bacterial infections.

Reference

Mutti, F.G., et al.: Adv. Syn. Cata., 354, 3409 (2012); Subudhi, B., et al.: Bull. Chem. Soc., Ethiopia., 26, 455 (2012)