Z-AEVD-FMK

For research use only. Not for therapeutic Use.

  • CAT Number: R060648
  • CAS Number: 1135688-47-9
  • Molecular Formula: C28H39FN4O10
  • Molecular Weight: 610.63
  • Purity: ≥95%
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Z-AEVD-FMK is a cleavable ADC linker for the synthesis of antibody active molecule conjugates (ADCs).


Catalog Number R060648
CAS Number 1135688-47-9
Synonyms

methyl (4S)-5-[[(2S)-1-[[(3S)-5-fluoro-1-methoxy-1,4-dioxopentan-3-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxo-4-[[(2S)-2-(phenylmethoxycarbonylamino)propanoyl]amino]pentanoate

Molecular Formula C28H39FN4O10
Purity ≥95%
InChI InChI=1S/C28H39FN4O10/c1-16(2)24(27(39)32-20(21(34)14-29)13-23(36)42-5)33-26(38)19(11-12-22(35)41-4)31-25(37)17(3)30-28(40)43-15-18-9-7-6-8-10-18/h6-10,16-17,19-20,24H,11-15H2,1-5H3,(H,30,40)(H,31,37)(H,32,39)(H,33,38)/t17-,19-,20-,24-/m0/s1
InChIKey CHZRBQFKZDGMTP-CDSYHYPYSA-N
SMILES CC(C)C(C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CCC(=O)OC)NC(=O)C(C)NC(=O)OCC1=CC=CC=C1

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