For research use only. Not for therapeutic Use.
Z-FG-NHO-BzOME is a cysteine protease inhibitor that selectively inhibits cathepsin B, cathepsin L, cathepsin S, and papain[1].
| Catalog Number | I040345 |
| CAS Number | 180313-86-4 |
| Synonyms | [[2-[[(2S)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoyl]amino]acetyl]amino] 4-methoxybenzoate |
| Molecular Formula | C27H27N3O7 |
| Purity | ≥95% |
| InChI | InChI=1S/C27H27N3O7/c1-35-22-14-12-21(13-15-22)26(33)37-30-24(31)17-28-25(32)23(16-19-8-4-2-5-9-19)29-27(34)36-18-20-10-6-3-7-11-20/h2-15,23H,16-18H2,1H3,(H,28,32)(H,29,34)(H,30,31)/t23-/m0/s1 |
| InChIKey | MWMGBOYXKWUFNQ-QHCPKHFHSA-N |
| SMILES | COC1=CC=C(C=C1)C(=O)ONC(=O)CNC(=O)C(CC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3 |
| Reference | [1]. Rajgopal Yadavalli, et al. Calpain-dependent endoproteolytic cleavage of PrPSc modulates scrapie prion propagation. J Biol Chem. 2004 May 21;279(21):21948-56. |
