Z-IETD-FMK

• CAT Number: I011539
• CAS Number: 210344-98-2
• Molecular Formula: C30H43FN4O11
• Molecular Weight: 654.68
• Purity: ≥95%
• Synonyms: methyl 5-[[1-[(5-fluoro-1-methoxy-1,4-dioxopentan-3-yl)amino]-3-hydroxy-1-oxobutan-2-yl]amino]-4-[[3-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-5-oxopentanoate
• Target: Caspase
• Solubility: >32.7mg/mL in DMSO
• Storage: Store at -20 C

Z-IETD-FMK (CAT: I011539) is a caspase inhibitor commonly used in laboratory research. It belongs to the class of peptide-based inhibitors that target caspases, which are enzymes involved in programmed cell death (apoptosis). Specifically, Z-IETD-FMK is a selective inhibitor of caspase-8, which plays a crucial role in the extrinsic apoptotic pathway. By inhibiting caspase-8, Z-IETD-FMK prevents its activation and subsequent downstream apoptotic signaling. This compound is often employed to study the involvement of caspase-8 in cellular processes and to explore potential therapeutic strategies targeting apoptotic pathways.