Z-Ile-Leu-aldehyde

• CAT Number: I002066
• CAS Number: 161710-10-7
• Molecular Formula: C20H30N2O4
• Molecular Weight: 362.46
• Purity: ≥95%
• Synonyms: benzyl ((2R,3R)-3-methyl-1-(((R)-4-methyl-1-oxopentan-2-yl)amino)-1-oxopentan-2-yl)carbamate
• Target: Notch
• Solubility: DMSO: ≥ 41 mg/mL
• Storage: Store at -20°C

Z-Ile-Leu-aldehyde (Cat.No:I002066) is a bioactive peptide aldehyde compound. It exhibits inhibitory properties against specific enzymes, making it relevant for enzymatic studies and potential therapeutic research. Researchers are investigating its role in various biochemical pathways, offering promising insights into its applications in drug development and biomedical research.

Reference

[1]. Schwarzer R, et al. Notch pathway inhibition controls myeloma bone disease in the murine MOPC315.BM model. Blood Cancer J. 2014 Jun 13;4:e217.
[2]. Schwarzer R, et al. Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed-Sternberg cells. Leukemia. 2012 Apr;26(4):806-13.
[3]. Okuhashi Y, et al. Gamma-secretase inhibitors induce erythroid differentiation in erythroid leukemia cell lines. Anticancer Res. 2010 Oct;30(10):4071-4.