Z-LEU-VAL-GLY-DIAZOMETHYLKETONE

• CAT Number: M016383
• CAS Number: 119670-30-3
• Molecular Formula: C22H31N5O5
• Molecular Weight: 445.52
• Purity: ≥95%
• Target: Anti-infection
• Storage: Desiccate at -20C
• IUPAC Name: benzyl N-[(2S)-1-[[(2S)-1-[(3-diazo-2-oxopropyl)amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate
• InChI: InChI=1S/C22H31N5O5/c1-14(2)10-18(26-22(31)32-13-16-8-6-5-7-9-16)20(29)27-19(15(3)4)21(30)24-11-17(28)12-25-23/h5-9,12,14-15,18-19H,10-11,13H2,1-4H3,(H,24,30)(H,26,31)(H,27,29)/t18-,19-/m0/s1
• InChIKey: KRMMQWXJLDORCJ-OALUTQOASA-N
• SMILES: CC(C)C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)C=[N+]=[N-])NC(=O)OCC1=CC=CC=C1

Z-Leu-Val-Gly-diazomethylketone（Cat No.:M016383）is a synthetic peptide-based inhibitor that selectively targets cysteine proteases, particularly caspase-3 and caspase-7, which play critical roles in apoptosis. By irreversibly binding to the active sites of these proteases, it effectively halts the apoptotic process, making it a valuable tool in studying cell death pathways and apoptosis-related diseases. Its ability to inhibit caspases has applications in research focused on neurodegenerative disorders, cancer, and inflammatory conditions, where dysregulated apoptosis is a factor. This inhibitor supports therapeutic research in modulating cell survival and death mechanisms.