For research use only. Not for therapeutic Use.
(Z)-Ligustilide(Cat No.:I018259)is a bioactive compound predominantly found in medicinal plants like Angelica sinensis (Dong Quai) and Ligusticum chuanxiong (Szechuan Lovage). Known for its therapeutic properties, (Z)-Ligustilide exhibits anti-inflammatory, neuroprotective, and antioxidant effects, making it valuable in traditional and modern medicine. It has been studied for its potential to alleviate symptoms related to pain, headaches, and circulatory issues by modulating cellular pathways involved in inflammation and oxidative stress. Its natural origin and pharmacological versatility make (Z)-Ligustilide a promising candidate for further research in drug development.
Catalog Number | I018259 |
CAS Number | 81944-09-4 |
Molecular Formula | C₁₂H₁₄O₂ |
Purity | ≥95% |
Target | Bacterial |
IUPAC Name | (3Z)-3-butylidene-4,5-dihydro-2-benzofuran-1-one |
InChI | InChI=1S/C12H14O2/c1-2-3-8-11-9-6-4-5-7-10(9)12(13)14-11/h5,7-8H,2-4,6H2,1H3/b11-8- |
InChIKey | IQVQXVFMNOFTMU-FLIBITNWSA-N |
SMILES | CCC/C=C\1/C2=C(C=CCC2)C(=O)O1 |
Reference | [1]. Rodrigues AMS, et al. The antifungal potential of (Z)-ligustilide and the protective effect of eugenol demonstrated by a chemometric approach. Sci Rep. 2019 Jun 19;9(1):8729. doi: 10.1038/s41598-019-45222-y<br>[2]. Ma H, et al. Z-ligustilide restores tamoxifen sensitivity of ERa negative breast cancer cells by reversing MTA1/IFI16/HDACs complex mediated epigenetic repression of ERa. Oncotarget. 2017 Apr 25;8(17):29328-29345. |