Z-LLNle-CHO

• CAT Number: M112003
• CAS Number: 133407-83-7
• Molecular Formula: C26H41N3O5
• Molecular Weight: 475.62
• Purity: ≥95%
• Synonyms: benzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxohexan-2-yl]amino]pentan-2-yl]amino]-1-oxopentan-2-yl]carbamate
• IUPAC Name: benzyl N-[4-methyl-1-[[4-methyl-1-oxo-1-(1-oxohexan-2-ylamino)pentan-2-yl]amino]-1-oxopentan-2-yl]carbamate
• InChI: InChI=1S/C26H41N3O5/c1-6-7-13-21(16-30)27-24(31)22(14-18(2)3)28-25(32)23(15-19(4)5)29-26(33)34-17-20-11-9-8-10-12-20/h8-12,16,18-19,21-23H,6-7,13-15,17H2,1-5H3,(H,27,31)(H,28,32)(H,29,33)
• InChIKey: RNPDUXVFGTULLP-UHFFFAOYSA-N
• SMILES: CCCCC(C=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1

Z-LLNle-CHO（Cat No.:M112003）is a potent peptide aldehyde inhibitor, commonly used in biochemical and pharmaceutical research. It features a Z (benzyloxycarbonyl) protecting group on the N-terminus, followed by the amino acid sequence LLNle, with Nle representing norleucine, a modified leucine. The aldehyde group at the C-terminus enables it to effectively inhibit enzymes such as proteases by interacting with their active sites. Z-LLNle-CHO is utilized primarily in protease inhibition studies, drug discovery, and the investigation of protein degradation pathways, particularly in cancer and metabolic disease research.