For research use only. Not for therapeutic Use.
Z1078601926(CAT: I040891) is an allosteric inhibitor of the human dopamine transporter (hDAT), which plays a key role in the regulation of dopamine levels in the brain. By binding to an allosteric site on hDAT, Z1078601926 modulates dopamine reuptake without directly competing with dopamine for the transporter binding site. It has shown synergistic effects when used in combination with Nomifensine (HY-B1110), an established dopamine reuptake inhibitor, enhancing the overall inhibition of dopamine transport. This compound can be used in research related to neurological diseases, particularly in the study of dopamine-related disorders such as Parkinson’s disease or depression, making it relevant for Neurological Disease Research.
| CAS Number | 1493256-85-1 |
| Synonyms | N-[1-(2-fluorophenyl)ethyl]-N-methylpyrrolidine-3-carboxamide |
| Molecular Formula | C14H19FN2O |
| Purity | ≥95% |
| IUPAC Name | N-[1-(2-fluorophenyl)ethyl]-N-methylpyrrolidine-3-carboxamide |
| InChI | InChI=1S/C14H19FN2O/c1-10(12-5-3-4-6-13(12)15)17(2)14(18)11-7-8-16-9-11/h3-6,10-11,16H,7-9H2,1-2H3 |
| InChIKey | VHKZXMHHYTZFNM-UHFFFAOYSA-N |
| SMILES | CC(C1=CC=CC=C1F)N(C)C(=O)C2CCNC2 |
