Z29077885

For research use only. Not for therapeutic Use.

  • CAT Number: I047739
  • CAS Number: 785710-21-6
  • Molecular Formula: C21H24N4O3S
  • Molecular Weight: 412.51
  • Purity: ≥95%
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Z29077885 is a potent serine/threonine kinase 33 (STK33) inhibitor with and IC50 value of 0.2367 μM and showed anticancer efficacy in various cancer cells. Z29077885 induces apoptosis via deactivation of the STAT3 signaling pathway, and induces cell cycle arrest at the S phase. Z29077885 is also an antiviral agent. The hydrochloride salt form Z29077885 (Axon 4142) is also available.
KEYWORDS: Z29077885 | Supplier | STK33 inhibitor | Z 29077885 | Z-29077885 | CAS [785710-21-6] | Non Selective | STK33 | Inhibitor | Enzymes | Lung cancer | Breast cancer


Catalog Number I047739
CAS Number 785710-21-6
Molecular Formula C21H24N4O3S
Purity ≥95%
IUPAC Name N-(1-propylbenzimidazol-2-yl)-3-pyrrolidin-1-ylsulfonylbenzamide
InChI InChI=1S/C21H24N4O3S/c1-2-12-25-19-11-4-3-10-18(19)22-21(25)23-20(26)16-8-7-9-17(15-16)29(27,28)24-13-5-6-14-24/h3-4,7-11,15H,2,5-6,12-14H2,1H3,(H,22,23,26)
SMILES CCCN1C2=CC=CC=C2N=C1NC(=O)C3=CC(=CC=C3)S(=O)(=O)N4CCCC4
Reference

NL Tran et al. Artificial intelligence-driven new drug discovery targeting serine/threonine kinase 33 for cancer treatment. Cancer Cell Int. 2023 Dec 12;23(1):321.

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