For research use only. Not for therapeutic Use.
Zaleplon selectively binds with high efficacy to the benzodiazepine site (ω1) on the α1 containing GABAA receptors; a nonbenzodiazepine hypnotic agent used in the treatment of insomnia
Catalog Number | R041957 |
CAS Number | 151319-34-5 |
Molecular Formula | C17H15N5O |
Purity | ≥95% |
IUPAC Name | N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethylacetamide |
InChI | InChI=1S/C17H15N5O/c1-3-21(12(2)23)15-6-4-5-13(9-15)16-7-8-19-17-14(10-18)11-20-22(16)17/h4-9,11H,3H2,1-2H3 |
SMILES | CCN(C1=CC=CC(=C1)C2=CC=NC3=C(C=NN23)C#N)C(=O)C |
Reference | D.J. Sanger et al. Comparison of the pharmacological profiles of the hypnotic drugs, zaleplon and zolpidem. Eur. J. Pharmacol. 1996, 313, 35-42.
S.M. Stahl et al. Selective actions on sleep or anxiety by exploiting GABA-A/benzodiazepine receptor subtypes. J. Clin. Psychiatry. 2002, 63, 179-180. |